If you're looking for a quaint and relaxing spot to enjoy happy hour, you've come to the right place. Main Street Wine Stoppe in Hannibal, MO offers an intimate cocktail lounge atmosphere, perfect for grabbing a drink after work, meeting friends or having a romantic date night. You'll never have to settle for a drink you don't like. Our local bar carries over 60 beers, 50 wines and an endless liquor selection.