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Dr Nimer has been studying the transcriptional regulation of normal and malignant hematopoiesis for decades, with the aim of understanding how the normal processes of stem cell self-renewal and differentiation are regulated and how these processes are aberrant in the myeloid malignancies. Overall, his lab has focused on defining genes that contribute to the development and progression of myelodysplastic syndromes (MDS) and acute myelogenous leukemia (AML) and on identifying novel ways to target ...

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