Contract Research Organization (CRO) providing DMPK, ADMET, LC-MS/MS & radio-immuno Bioanalysis, Quality control service

Methods development, validation, transfer and cross-site validation Sample processing including small molecules, proteins and oligonucleotides Sample cleanup techniques:Analysis: LC-UV, LC-UV-MS and LC-UV-MS/MS Protein precipitation Liquid-Liquid extraction Solid phase extraction Online sample cleanup Complete bioanalytical report writing ( preliminary and final reports) and document handling In vitro AssaysIn vitro Assays Absorption, Distribution & Metabolism; Radio-immunoassays Safety Assess...

Methods development, validation, transfer and cross-site validation Sample processing including small molecules, proteins and oligonucleotides Sample cleanup techniques:Analysis: LC-UV, LC-UV-MS and LC-UV-MS/MS Protein precipitation Liquid-Liquid extraction Solid phase extraction Online sample cleanup Complete bioanalytical report writing ( preliminary and final reports) and document handling In vitro AssaysIn vitro Assays Absorption, Distribution & Metabolism; Radio-immunoassays Safety Assessment Off-Target Pharmacology (in vitro): Screening against enzymes, receptors and ion channels, Phospholipidosis, Cardiac Toxicity, Cytotoxicity and Geneotoxicity (AMES). In vivo DMPK Toxicology oral /intravenous dosing bioavailability rodent and higher species determin clearance, half-life, Tmax..