City of Hope | Simi Valley provides the community with unparalleled cancer care and innovative treatments close to home. The accessible location of City of Hope's Simi Valley practice, near the 118 and 23 freeways, puts our patients within easy reach of additional laboratory and radiology services, offering convenience when traveling between appointments. Our bright and modern facility offers multiple exam and treatment rooms for patient comfort and convenience, expanding access to City of Hope's world-class level of care. Our skilled staff specializes in medical oncology, blood disorders and cancers. We also offer consultations and second opinions.