The Sampson Laboratory

Beyond providing unmatched clinical care at Boston Children's, we're working around the clock to design approaches that let kids be kids. The overall goal of the Sampson Lab is to help improve the health of children with nephrotic syndrome through ap...

Beyond providing unmatched clinical care at Boston Children's, we're working around the clock to design approaches that let kids be kids. The overall goal of the Sampson Lab is to help improve the health of children with nephrotic syndrome through applied genomics, with a focus on samples and data collected from patients with this condition. We use computational genomics and bioinformatics to discover new, and map known, nephrotic syndrome-associated variants. We use systems genomics to integrate this genetic data with other genome-scale molecular datasets to try to understand the mechanisms linking these genetic changes with disease. And we use epidemiology to discover the clinical consequences for patients carrying disease-associated genetic variants.